Welcome addresses, the Director of the Institut Pasteur Stewart COLE and members of the organizing committee

Developing a controlled human infection model for TB

Transmission and evolution of MDR Mycobacterium tuberculosis complex strains

Cis-regulatory effects of constitutive and context-specific intercellular mosaic methylation in M. tuberculosis

Mycobacterial diversity’s lens on public health

Epistasis defines the transmission fitness of multidrug-resistant Mycobacterium tuberculosis

Fast RNA-based drug susceptibility testing fills the gap between slow phenotypic and ultra-fast DNA-based resistance detection

Finding the most "essential" essential genes in M. tuberculosis

ADP-ribosylation of DNA in Mycobacterium tuberculosis – from “How” to “Why?”

TbD1 deletion in Mycobacterium tuberculosis adaptation to the human host

Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex

Mycobacterial determinants of intrinsic multidrug tolerance and resistance

It’s about time:  Antibiotic resilience as a driver of treatment failure in tuberculosis

Exploring horizontal gene transfer in predominantly clonal tuberculosis-causing mycobacteria

The Mycobacterium tuberculosis protein O-phosphorylation landscape

Pheno-tuning: A strategy to undermine mycobacterial cells

OPTIKA, a new high content in vitro kill-kinetic assay to evaluate the efficacy of novel anti-TB drug combinations

Targeted protein self-degradation as a novel therapeutic strategy for tuberculosis

Sanfetrinem Cilexetil - From (re-) discovery to clinical trial

Design Principles of Combination Therapies for TB 

Mycobacterial growth control in natural vs vaccine induced protection

A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis diagnosis

Mycobacterial virulence and macrophage mitochondrial metabolism face off

Human Antibodies Targeting a Transporter Mediate Protection Against Tuberculosis

Roles of antibody characteristics in the protection against TB - from epitope to Fc and isotype significance

BCG::ESAT6-PE25SS – a new recombinant BCG strain – insights into delivery and protective mechanisms

MTBVAC from the lab to clinical efficacy trials, the moment of truth 100 years after BCG

Mind the Gap: Functional Characterisation of the Mycobacterial Virulence Protein Erp

ESX-1-proficient BCG vaccines: challenges and opportunities

Mycobacterial resistance to metal stress during infection

Pre-existing heterogeneity of inducible nitric oxide synthase expression drives differential growth of Mycobacterium tuberculosis in macrophages

Is Mycobacterium tuberculosis the greatest cell biologist in the world?

Making mistakes in the goldilocks zone: mistranslation as a novel form of mycobacterial virulence

Drivers of diversity in tuberculosis in vivo

One Health analysis of Mycobacterium bovis

Drosophila melanogaster as a host model to study mycobacterial host-pathogen interactions

Implementation of a cynomolgus macaque model of tuberculosis

Efficacy of TB regimens in an NHP model: focusing on pathology

Mycobacterium abscessus fitness modulation in vivo: a bacterial trait or ... a bacterial trait

The small RNA B11 is a master regulator of ESX-4 secretion and M. abscessus pathogenesis

A drug candidate against Mycobacterium abscessus and other cystic fibrosis pathogens

Unpacking the molecular determinants of Mycobacterium abscessus infections

M. orygis: zTB’s missing link

Exploiting MAP-kinase signaling as a host directed target in tuberculosis

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis

Targeting human macrophages to improve the efficacy of anti-TB drugs

Host regulators of phagosomal membrane integrity in TB infection

Neutrophil-driven immunosuppressive feedback loops underlying susceptibility to M. tuberculosis

Is intracellular activity a potent driver for novel TB drug development?

Exploiting a Bacterial Enzyme for Selective Prodrug Activation: Mycobacterium tuberculosis N-acetylates 5-aminomethyl oxazolidinones

Expression of a novel mycobacterial phosphodiesterase successfully lowers cAMP levels resulting in reduced tolerance to cell-wall targeting antimicrobials

Targeting mycolic condensation enzymes: from screens to insights

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis

Novel insights into mycobacterial cell division mechanisms using C. glutamicum as a model organism

Compartment-specific proximity labeling uncovers the exposure of Type VII ESX secretion system substrates to the mycobacterial periplasm

Structure and dynamics of a mycobacterial type VII secretion system

Human Genetics of tuberculosis : the TYK2 story

Systems immunomonitoring to support development of new treatments and vaccines for TB

Transcriptional signatures reveal the immune response underlying progression and pathogenesis in tuberculosis

Using Biomarkers to Predict TB Treatment Duration

Drugs hug, bugs chug - genetic-chemical synergy in mycobacteria

Closing comments / End of congress